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Synthesis Reagents(10) - List of Manufacturers, Suppliers, Companies and Products

Last Updated： Aggregation Period:Sep 24, 2025～Oct 21, 2025
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Synthesis Reagents Product List

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Introduction to Custom Monoclonal Antibody Production Service Case Studies vol. 10

Introduction to Custom Monoclonal Antibody Production Service Case Studies vol. 10

It is possible to design fine antigens! An article introducing an example of antibody production that distinguishes a single amino acid substitution.

Antibody artisans perform selection in vitro against fixed antigens without using animal immunity. As a result, it is possible to conduct binding reactions in the state or environment where peptides or proteins are prepared, allowing for detailed antigen design, such as narrowing down the area of interest. Here, we will introduce an example of producing an antibody that can distinguish a substitution of one amino acid within a specific sequence. We encourage you to read on. [Contents] 1. Preparation of Antigens - 1-1. Narrowing down the target area - 1-2. Setting up antigens including negative controls - 1-3. Synthesizing peptides 2. Selection to Increase Specificity - 2-1. Excluding antibodies that bind to ends, etc. - 2-2. Increasing selection pressure with multiple antigens 3. Selection of Antibodies - 3-1. Checking the signal-to-noise ratio with ELISA - 3-2. Confirming the nucleotide sequence of the antibody 4. Summary *For detailed content of the article, please refer to the related links. *For detailed specifications, please refer to the PDF materials or feel free to contact us.

  • Other services
  • Other contract services
  • Contract manufacturing

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Long-chain RNA synthesis (mRNA contract synthesis service)

Long-chain RNA synthesis (mRNA contract synthesis service)

Synthesis of long-chain RNA using in vitro transcription method! Plasmid clones can also be used as templates.

At Fasmac, we offer "long-chain RNA synthesis." We synthesize RNA through in vitro transcription using T7 polymerase from template DNA (prepared from plasmid clones via PCR or oligo DNA), followed by purification with silica columns. The purity and yield are confirmed through absorbance measurement and electrophoresis. Please contact us with your desired sequences for various applications such as RT-PCR amplification control RNA, gRNA for genome editing, small RNA, mRNA preparation, RNA aptamers, etc. 【RNA Usage Examples】 ■ RNA of the GFP gene sequence was synthesized, and after adding a 5' cap and polyA-tail, it was introduced into cultured cells using the lipofection method. ■ Green fluorescence was observed approximately 5 hours after introduction. *For more details, please refer to the PDF materials or feel free to contact us.

  • Contract Analysis
  • Contract Analysis
  • Analysis Services

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Contract services for research - peptide synthesis

Contract services for research - peptide synthesis

Unrefined products will be shipped within a minimum of 3 business days, and refined products will be shipped within a minimum of 5 business days.

Bex Corporation offers peptide synthesis services. We provide a wide range of modifications including various fluorescent modifications, phosphorylation, amidation, acetylation, conjugation, and cyclization. Our staff, who are well-versed in organic synthesis, carefully synthesize each peptide one by one in our in-house lab. We have extensive experience with high-difficulty peptides, so please feel free to consult our staff. 【Features】 ■ Wide range of support ■ Careful synthesis of each peptide in our in-house lab ■ Extensive experience with high-difficulty peptides *For more details, please refer to our catalog or feel free to contact us.

  • Custom reactions and synthesis
  • Peptide synthesis

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Fasmac: Artificial Gene Synthesis

Fasmac: Artificial Gene Synthesis

Everything from order receipt to manufacturing is done within Japan! We significantly reduce the time and effort our customers spend on complicated tasks.

We would like to introduce the artificial gene synthesis from Fasmac Co., Ltd., which we handle. The synthesized sequences will be delivered in a plasmid form after being introduced into a vector as double-stranded DNA. In addition to the standard pUC series vectors from the company, we can also accommodate cloning into specified vectors provided by you. All processes from order to manufacturing are conducted domestically in Japan, and our specialized staff will respond quickly and meticulously. This significantly reduces the time and effort our customers spend on complicated tasks such as PCR, cloning, and sequencing analysis. 【Service Items】 ■ Express Course - Up to 1,500 bp / 1,501 to 3,000 bp / 3,001 to 4,000 bp ■ Standard Course - Up to 1,500 bp / 1,501 to 3,000 bp / 3,001 to 4,000 bp - 4,001 to 6,000 bp / 6,001 to 10,000 bp *For more details, please refer to the PDF document or feel free to contact us.

  • Analytical Equipment and Devices

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Introduction to Custom Monoclonal Antibody Production Service Case Studies vol. 9

Introduction to Custom Monoclonal Antibody Production Service Case Studies vol. 9

Not mediated by animal immunity! An article introducing successful cases of antibodies that distinguish specific oxidized Cys.

DJ-1 is a 21 kDa protein, and we present a successful case of producing antibodies that specifically recognize the oxidized form of the Cys residue at position 106 (C106) of DJ-1. We have attempted to obtain antibodies that specifically recognize the oxidized C106 through the production of polyclonal antibodies via immunization in rabbits and monoclonal antibodies via immunization in mice, but we were unable to obtain the desired antibodies in either case. Here, we introduce a method for producing antibodies that do not involve animal immunization and are selected entirely in vitro, along with the results of verifying the specificity of the obtained antibodies. 【Contents】 ■1. What is DJ-1 ■2. Strategic Screening 　・2-1. Antigen Design 　・2-2. Panning and ELISA Screening 　・2-3. Cross-reactivity Confirmation by ELISA ■3. Western Blotting and Immunoprecipitation ■4. Summary *For detailed content of the article, please refer to the related links. *For detailed specifications, please refer to the PDF document or feel free to contact us.

  • Other services
  • Other contract services
  • Contract manufacturing

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Announcement of the Establishment of the Nucleic Acid Medicine API Development Center

Announcement of the Establishment of the Nucleic Acid Medicine API Development Center

[Announcement of New Base Establishment] Opening of a new GMP manufacturing facility for oligonucleotides.

Ajinomoto Bio-Pharma Services and Gene Design will strengthen its contract development and production system from the early stages of development to late stages and market launch by introducing large-scale production facilities. With the establishment of the new site, the production volume per lot will expand to the kilogram level. By combining our production capacity with the mass production technology of the Ajinomoto Group, a flexible and seamless supply system will be established, transitioning from conventional μg manufacturing to over 100 kg. [Overview] - Newly established within the research facility in Ibaraki City, Osaka Prefecture - Combined with the mass production technology of the Ajinomoto Group (AJIPHASE technology) - Establishing a supply system from conventional μg to over 100 kg *For more details, please refer to the PDF document or feel free to contact us.

  • Other contract services
  • Contract manufacturing

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Novabiochem(R) Peptide Synthesis Reagent Product Guide

Novabiochem(R) Peptide Synthesis Reagent Product Guide

The product specifications for 20 standard Fmoc amino acids have been renewed!

This catalog is a product guide for the high-quality brand of peptide synthesis reagents, "Novabiochem(R)." By setting stricter product standards for standard Fmoc amino acids used in peptide synthesis, we have made it possible to use our products with greater confidence, from basic research to pharmaceuticals, cosmetics, and contract synthesis. We offer a wide range of packaging options, from small sizes to bulk sizes. [Contents (excerpt)] ■ Major Fmoc amino acids ■ Pseudoproline dipeptides ■ Coupling agents ■ Resins for solid-phase synthesis ■ History of Novabiochem innovations *For more details, please refer to the PDF document or feel free to contact us.

  • others

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Monoclonal Antibody Production Contract Service Prices

Monoclonal Antibody Production Contract Service Prices

The price is based on standard antibody production costs. A precise estimate will be provided after consultation for each project, considering the most efficient process.

Antibody Production Pricing Standard Antibody Production = ¥1,800,000 per antigen Provision of 1 to 5 candidate antibodies (200μg each) from which the customer can select the final antibody, provided at 1mg (Myc-His tagged, ELISA positive). Additional Sequencing = ¥50,000 per 10 clones Additional sequencing for the same antigen. *The standard price includes sequencing for 10 clones. Additional Candidate Antibodies = ¥50,000 per candidate antibody Additional candidate antibodies for customer confirmation against the same antigen (200μg each). *The standard price includes delivery of up to 5 clones. Additional Final Antibody Production = ¥70,000 per 1mg Additional production of final antibodies for the same antigen simultaneously. *The standard price includes delivery of 1 clone (1mg). *For more details, please refer to the PDF document or feel free to contact us.

  • Other contract services
  • Other services

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Chemical synthesis: Contract synthesis of short-chain peptides

Chemical synthesis: Contract synthesis of short-chain peptides

Contract synthesis of short peptides! Also compatible with the synthesis of peptides with protecting groups.

We actively conduct contract synthesis of short-chain peptides (2 to 5 amino acids). We have numerous synthesis achievements of over 10g. We offer catalog sales for relatively simple structures such as dipeptides and tripeptides. Additionally, we can accommodate large-scale synthesis of short-chain peptides, which is difficult to handle with solid-phase synthesis, through liquid-phase synthesis. 【Lineup (excerpt)】 ■ Fluorescently labeled peptides ■ Enzyme substrate peptides ■ Functional short-chain peptides ■ Imidazole dipeptides *For more details, please refer to the PDF document or feel free to contact us.

  • Other contract services

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Monoclonal antibody production contract service option

Monoclonal antibody production contract service option

Improvement of affinity after antibody production

Improvement of Affinity After Antibody Production The antibodies obtained through the Antibody Artisan's contract services come with various optional services. The Antibody Artisan offers services to further enhance the affinity of the produced antibodies. In the HuCAL PLATINUM library, each CDR region can be freely replaced like a cassette, and by combining this with high-speed screening technology, it is possible to rapidly improve the affinity of antibodies by 10 to 1,000 times. Please inquire for pricing details. *This is an optional service for antibodies produced through the Antibody Artisan service. *This menu is not applicable to antibodies you already possess. *For more details, please refer to the PDF materials or feel free to contact us.

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Monoclonal antibody production contract option service

Monoclonal antibody production contract option service

Format conversion

Format Conversion The antibodies obtained through the Antibody Artisan's contract services come with various optional services. If an Fc region is required, we can convert the candidate antibody's Fab into full-length human, human-mouse chimeric, or human-rat chimeric forms, and deliver purified IgG molecules within 10 weeks. After cloning the genes for the VH and VL regions along with the desired constant region into a vector, we simultaneously introduce the light chain and heavy chain vectors into mammalian cells for expression. For more details, please also refer to the selection of antibody formats in the service flow. For pricing, please inquire for confirmation. *This is an optional service for antibodies produced through the Antibody Artisan service. *This menu is not applicable to antibodies you already possess. *For more details, please refer to the PDF materials or feel free to contact us.

  • Other contract services
  • Other services

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